Here’s a clear, lab friendly routine you can use between annual calibrations to stay confident in your data: 1. Start with the right environment Draft‑free room, constant temperature between 15–30 °C with no more than ±0.5 °C variation during the test. Use a balance with draft protection and an evaporation trap, plus a ...
In most labs, pipettes are used thousands of times a day, but technique is almost never revisited. A few microliters off can flatten your standard curves, destroy reproducibility, and make you question perfectly good science. Here are the key principles of correct pipette operation (air-displacement pipettes): Set the volume properly: always approach the desired ...
Transcriptional regulation is a key component in the downstream response to neuronal stimulation. Although several techniques exist to identify active neurons, however, there is currently no method available to estimate neuronal activity from whole transcriptome gene expression data. A recent study introduces NEUROeSTIMator, a powerful and broadly applicable bioinformatics tool that quantifies neuronal activation. ...
Are you exploring spatial genomics and wondering which 10x Genomics platform best fits your research needs? Here’s a quick guide to the key differences and ideal use cases for Visium and Xenium. Visium Spatial Gene Expression Visium enables unbiased, whole-transcriptome spatial gene expression profiling. It maps the location of thousands of RNA transcripts ...
We're excited to spotlight a landmark study that leveraged 10x Genomics single-cell technology to identify the key human cell factors required for SARS-CoV-2 infection. Scientific Context: Understanding which host genes and pathways enable SARS-CoV-2 to infect human cells is crucial for developing targeted therapies and improving our response to COVID-19. This study set ...
We’re excited to highlight a landmark study that used spatial transcriptomics to map the molecular and cellular landscape around amyloid plaques in Alzheimer’s disease (AD). Scientific Context: The study aimed to dissect how different brain cell types interact and respond to amyloid plaque accumulation—a central feature of AD. By integrating spatial transcriptomics and ...
We’re excited to spotlight a groundbreaking study that leveraged cutting-edge 10x Genomics technology to chart the cellular and gene expression landscape of the developing human heart at single-cell resolution. Scientific Context: The study aimed to unravel how gene expression and cell types are organized during early human heart development. By combining spatial transcriptomics, ...
A new benchmarking study has set the standard for evaluating high-throughput, subcellular spatial transcriptomics technologies—critical tools for understanding complex tissue biology in cancer and beyond. “Systematic Benchmarking of High-Throughput Subcellular Spatial Transcriptomics Platforms” How Did 10x Genomics Platforms Perform Against the Competition? Visium HD (FFPE and Fresh Frozen): Visium HD from 10x Genomics ...
Excited to share a landmark study that leveraged 10x Genomics technologies to unravel the cellular architecture and immune landscape of human cutaneous squamous cell carcinoma (cSCC). “Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma” How did 10x Genomics power this research study? Chromium Single Cell Analysis: Enabled high-throughput single-cell ...
Tired of counting cells with a hemocytometer? Tired of inconsistent results and handwritten notes? The CellDrop uses a patented, wipe-clean, variable-height chamber that replaces hemocytometers and disposable plastic slides, making your workflow more sustainable and eliminating tedious preparation. Fast, accurate, and easy to use No consumables = less waste Consistent, standardised counts across ...
