Adaptive amplification continues to evolve as a key approach to improving data quality in next generation sequencing workflows. With the introduction of icon16, n6 extends its AutoNorm technology to laboratories working with lower throughput applications, enabling more flexible and scalable library preparation. icon16 brings the same core principles as iconPCR, applying real time monitoring ...
Spatial biology technologies continue to transform how researchers study tissues in their native context. By preserving spatial information, these approaches allow scientists to understand how cellular organization and molecular interactions shape biological function and disease. The Xenium platform from 10x Genomics already enables high resolution spatial transcriptomics through in situ detection of RNA ...
Here’s a clear, lab friendly routine you can use between annual calibrations to stay confident in your data: 1. Start with the right environment Draft‑free room, constant temperature between 15–30 °C with no more than ±0.5 °C variation during the test. Use a balance with draft protection and an evaporation trap, plus a ...
In most labs, pipettes are used thousands of times a day, but technique is almost never revisited. A few microliters off can flatten your standard curves, destroy reproducibility, and make you question perfectly good science. Here are the key principles of correct pipette operation (air-displacement pipettes): Set the volume properly: always approach the desired ...
Transcriptional regulation is a key component in the downstream response to neuronal stimulation. Although several techniques exist to identify active neurons, however, there is currently no method available to estimate neuronal activity from whole transcriptome gene expression data. A recent study introduces NEUROeSTIMator, a powerful and broadly applicable bioinformatics tool that quantifies neuronal activation. ...
We're excited to spotlight a landmark study that leveraged 10x Genomics single-cell technology to identify the key human cell factors required for SARS-CoV-2 infection. Scientific Context: Understanding which host genes and pathways enable SARS-CoV-2 to infect human cells is crucial for developing targeted therapies and improving our response to COVID-19. This study set ...
We’re excited to spotlight a groundbreaking study that leveraged cutting-edge 10x Genomics technology to chart the cellular and gene expression landscape of the developing human heart at single-cell resolution. Scientific Context: The study aimed to unravel how gene expression and cell types are organized during early human heart development. By combining spatial transcriptomics, ...
Excited to share a landmark study that leveraged 10x Genomics technologies to unravel the cellular architecture and immune landscape of human cutaneous squamous cell carcinoma (cSCC). “Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma” How did 10x Genomics power this research study? Chromium Single Cell Analysis: Enabled high-throughput single-cell ...
